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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Pain. 2015 Apr;156(4):722–730. doi: 10.1097/j.pain.0000000000000104

Figure 5. Increased nociceptive signaling in the spinal cord of sickle mice.

Figure 5

Protein bands (and molecular weight) of phosphorylated and total proteins determined using Western immunoblotting and their densitometric profiles are shown for JNK (A), p38 (B), and p44/p42 ERK (C). Density of phosphoprotein bands relative to their specific total protein are shown. Data are expressed as mean ± SEM from 5 mice per group of 5 separate experiments. Statistical significance is denoted by *P < 0.05 and **P < 0.005. Mean age of mice ± SEM in months were 4.04 ± 0.29 for HbAA-BERK and 4.38 ± 0.32 for HbSS-BERK.