Skip to main content
. 2015 Mar 19;10(3):e0119771. doi: 10.1371/journal.pone.0119771

Fig 13. Proposed schematic summary of the biosynthesis of DPA and its translocation to Arabinoglactan synthesis site.

Fig 13

The figure shows the various cell wall components MA (Mycolic Acids), AG (Arabinogalactan), PG (Peptidoglycan), PM (Plasma Membrane) and LAM (Lipoarabinomannan). The epimerase complex, DprE1-DprE2 is involved in conversion of DPR to DPA through the intermediate DPX. DPR is synthesized from D-glucose-1-phosphate, through a series of biosynthetic steps. DPA serves as an arabinose donor in the cell wall and is formed by epimerization by DprE1 (Rv3790) and DprE2 (Rv3791). Rv2073c is a short chain dehydrogenase (249 residues) which shows interaction with DprE2.