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. 2015 Mar;148(2):82–89. doi: 10.1177/1715163515570111

Table 3.

Treatment failures2,5,11,20,21

Public Health Agency of Canada Treatment to be guided by antimicrobial susceptibility testing in consultation with infectious disease specialists and local public health authorities, with test of cure by culture collected 3 to 7 days following completion of treatment.
Public Health Ontario A higher dose of ceftriaxone should be used with azithromycin, e.g., ceftriaxone 1 g IM plus azithromycin 2 g PO each as a single dose (first-line treatment recommended if not initially used).
US Centers for Disease Control Ceftriaxone 250 mg IM plus azithromycin 2 g PO each as a single dose.
UK, Europe Alternative regimens as outlined in Table 1, with review of local and national resistance trends.