Table 3.

Metabolic parameters investigated at 12 weeks after ovariectomy

Parameters	Normal diet		High-fat diet
	Sham	OVX	Sham	OVX
Body weight (g)	284.28 ± 3.68	336.87 ± 4.81*	342.22 ± 4.93*	419.50 ± 4.56*†‡
Visceral fat (g)	12.20 ± 0.51	16.26 ± 1.13*‡	31.14 ± 1.62*†	35.20 ± 0.94*†‡
Uterus weight (g)	0.39 ± 0.02	0.10 ± 0.00*‡	0.45 ± 0.03†	0.10 ± 0.00*‡
Glucose (mg%)	124.27 ± 5.79	130.67 ± 7.84	135.03 ± 5.60	160.84 ± 5.93 *†‡
Cholesterol (mg%)	88.72 ± 5.84	106.74 ± 10.06	125.63 ± 13.5*†	156.75 ± 11.8*†‡
Triglyceride (mg%)	31.60 ± 3.25	32.47 ± 2.10	31.70 ± 3.01	31.58 ± 3.07
Insulin (ng/ml)	0.87 ± 0.14	1.57 ± 0.27*	1.57 ± 0.25*	1.58 ± 0.11*
HOMA index	5.21 ± 0.40	11.74 ± 2.01*	11.92 ± 2.27*	12.90 ± 1.91*
Estradiol level (pg/ml)	127.65 ± 20.95	62.37 ± 7.23*‡	129.37 ± 8.16†	74.37 ± 7.11*‡
Serum MDA (μmol/ml)	3.52 ± 0.16	4.31 ± 0.14*	3.99 ± 0.12*	4.80 ± 0.16*†‡
Cardiac MDA (μmol/ml)	5.76 ± 0.96	13.41 ± 1.50*	12.09 ± 2.35*	11.69 ± 2.01*
Food intake (gram/day)	13.21 ± 0.97	14.29 ± 0.77	15.91 ± 0.50*	16.30 ± 0.58*

Values are mean ± SE for six rats per group

OVX ovariectomized, HOMA homeostasis model assessment, MDA malondialdehyde

*P < 0.05 vs. NDS, †P < 0.05 vs. NDO, ‡P < 0.05 vs. HFS