Table 4b. Comparison at different thresholds between imaging and combined grades.

Cutoff	κ	Sensitivity	CI	Specificity	CI	LR+	CI	LR−	CI
Proliferative vs non-proliferative	0.697	0.79	0.72–0.85	0.97	0.96–0.97	23.94	18.42–31.12	0.22	0.16–0.29
Non-STDR vs sight-threatening DR	0.540	0.81	0.78–0.83	0.75	0.72–0.77	3.17	2.86–3.52	0.26	0.22–0.30
CSMO vs no CSMO	0.624	0.72	0.67–0.77	0.94	0.93–0.95	11.95	9.83–14.54	0.29	0.24–0.36
Any maculopathy vs no maculopathy	0.512	0.70	66–0.73	0.82	0.80–0.84	3.95	3.49–4.47	0.37	0.33–0.41

Abbreviations: CI, confidence interval; LR+ and LR−, positive and negative likelihood ratios.

N=1963 for retinopathy; N=2110 for maculopathy with 27 missing data.