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. Author manuscript; available in PMC: 2015 Mar 20.
Published in final edited form as: J Long Term Eff Med Implants. 2014;24(4):259–265. doi: 10.1615/jlongtermeffmedimplants.2014010562

Table.

Pattern Recognition Receptors are presented according to their localization

Pattern Recognition Receptors
Membrane-bound PRRs Cytoplasmic PRRs
Toll-like Receptors (TLRs) NOD-like receptors

  • NOD

  • NALPs
C-type lectin Receptors (CLRs)

  • Mannose receptors

  • Asialoglycoprotein receptor family

RIG-I-like receptors (RLRs)

Four different classes of pattern recognition receptor (PRR) families have been identified. These PRRs are expressed in macrophages and dendritic cells and also in various immune cells. They include transmembrane proteins such as the Toll-like receptors (TLRs), and C-type lectin receptors (CLRs). Cytoplasmic proteins are the NOD-like receptors (NLRs), and Retinoic acid inducible gene (RIG)-I-like receptors (RLRs).