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. Author manuscript; available in PMC: 2015 Mar 20.
Published in final edited form as: FEBS J. 2013 Nov 13;281(1):129–145. doi: 10.1111/febs.12581

Figure 2.

Figure 2

clustalW2 multiple sequence alignment (www.ebi.ac.uk/Tools/msa/clustalw2/) of selected l-threonine aldolases with different specificities: Escherichia coli TA (eTA) and Thermotoga maritima TA (tTA) are low-specificity threonine aldolases with a marked preference for l-allo-threonine; Aeromonas jandaei TA (ajTA) shows an absolute preference for l-allo-threonine; Pseudomonas aeruginosa (paTA) shows no preference for l-threonine isomers. Alignment symbols: “*” conserved residue in all sequences; “:” conserved substitution; “.” semi-conserved substitution. The amino acid residues mutated in the present study are shown in bold red character.