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Glucose stimulated insulin secretion on isolated islets of langerhans. Values are mean ± SEM for 8 cups (2 cups each containing 5 islets for each condition from each animal; 4 animals in each group); * P < 0.05 statistically significant differences between adult (4- month- old) and old (12- month- old). #P<0.05, statistically significant differences between inhibitor and glucose 16.7 mM/l
