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. 2015 Apr;43(4):611–619. doi: 10.1124/dmd.114.062877

Fig. 7.

Fig. 7.

Graphical summary. Glucuronidation activity in the normal kidney is governed by UGT1A9, UGT2B7, and to a lesser extent by UGT1A6. However, UGT expression and glucuronidation activity are significantly reduced in tumor kidney tissues, with potential clinical implications for disease treatment.