TABLE 3.
Glucuronidation activity of kidney homogenate samples for listed probe substrates
| Substrate | Normal |
Tumor |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Min | Max | Average | S.D. | CV | Min | Max | Average | S.D. | CV | |
| % | % | |||||||||
| Deferiprone-G (nmol/min per mg) | 0.7 | 6.2 | 1.7 | 1.5 | 86 | 0.01 | 2.4 | 1.1 | 0.8 | 69 |
| Propofol-G (area/min per mg) | 0.2 | 7.5 | 3.1 | 2.2 | 69 | 0.01 | 1.5 | 0.4 | 0.4 | 109 |
| Sorafenib-G (area/min per mg) | 33 | 19133 | 6558 | 5940 | 91 | 0 | 8083 | 1257 | 2295 | 183 |
| MPA-G (pmol/min per mg) | 1.0 | 318 | 147 | 106 | 72 | 0.1 | 104 | 23 | 31 | 134 |
| AZT-G (pmol/min per mg) | 0.01 | 102.0 | 35.1 | 31.4 | 89 | 0.00 | 2.2 | 0.4 | 0.6 | 160 |
CV, coefficients of variation.