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. 2015 Mar 20;5:9344. doi: 10.1038/srep09344

Figure 3. EPAC2 activation by cAMP in the absence and presence of ESI-09 or HJC0726.

Figure 3

Dose-dependent activation of EPAC2 by cAMP in the absence of inhibitor (A), or in the presence of 5 µM ESI-09 (B) or 1 µM HJC0726 (C). (D) Relative EPAC2 GEF activity as a function of cAMP concentration.