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. 2015 Mar 20;5:9374. doi: 10.1038/srep09374

Figure 5. Distinct type I and type II TA modules impact fitness of intracellular S. Typhimurium in fibroblasts and epithelial cells.

Figure 5

Shown are the survival rates of S. Typhimurium mutants lacking the indicated type I (grey bars) and type II (white bars) TA modules. (a) ratio of viable intracellular bacteria at 24 h and 2 h post-infection in human BJ5ta fibroblasts; (b) ratio of viable intracellular bacteria at 16 h and 2 h post-infection in human HeLa epithelial cells. “Δ5” refers to the Δhok-sokST ΔtisB-istRST ΔldrA-ldrAST Δta4ST ΔvapBC2ST mutant. Data are the means and standard deviations from three independent experiments. *, P = 0.01 to 0.05; **, P = 0.01 to 0.001; ***, P = < 0.001, by one-way ANOVA with Dunnett's post-test.