Table 2.
Intraoperative data.
| Variables | Reparixin (n = 16) | Placebo (n = 16) | P-value |
|---|---|---|---|
| Number of grafts | 0·27* | ||
| Two | 4 (25) | 2 (12·5) | |
| Three | 10 (62·5) | 14 (87·5) | |
| Four | 2 (12·5) | 0 (0) | |
| Time aortic clamping (min) | 52 (35;71) | 61 (46;72) | 0·564† |
| CPB time (min) | 95 (66;110) | 94 (74;113) | 0·491† |
| Anaesthesia time (min) | 290 (280;327) | 347 (318;374) | 0·017† |
| Total of Ringer's lactate (ml) | 1100 (1000;1838) | 1550 (1075;2500) | 0·043† |
| Fluid balance (ml) | 2575 (2027;3080) | 3200 (2928;3778) | 0·029† |
| Maximum noradrenaline ≥ 0·11 μg kg−1 min−1 | 3 (18·8) | 8 (50) | 0·063* |
| Use of dobutamine | 4 (25) | 8 (50) | 0·14* |
*
Fisher's exact or χ2 tests
†
Mann-Whitney U-test. Given are median with interquartile range (IQR) or absolute numbers (percentages); min = minutes; CBP= cardiopulmonary bypass.