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. 2015 Mar 12;49(2):177–179. doi: 10.4132/jptm.2015.02.04

Fig. 1.

Fig. 1.

Representative macroscopic and microscopic images of the lesion. (A) The middle portion of umbilical cord is focally enlarged, inside which an ill-defined white to brown horseshoe-shaped area (arrowhead) surrounding the umbilical vessels is noted. (B) The concentrically laminated, round-ovoid, basophilic calcified bodies, referred to as Michaelis-Gutmann bodies, are seen within macrophages (arrowhead). (C) This lesion is composed of multiple, small, round to oval, calcified bodies (calcospherites), Michaelis-Gutmann bodies (arrowheads), and an inflammatory infiltrate containing mainly necrotic macrophages. (D) The Michaelis-Gutmann bodies (arrowheads) are also observed in the noncalcified area.