TABLE 3.
Data for sets of shRNA-PAK1 and shRNA-ARF6 in both stages of neurons
Ctrl, control.
| Stage | Sample name | No. of spines/10 μm (mean ± S.E.) | Percent differences (mean ± S.E.) | n (no. of coverslips) | No. of neurons | No. of dendrites |
|---|---|---|---|---|---|---|
| Developing | Ctrl vector + HA | 4.43 ± 0.10 | 0 ± 2.33 | 8 | 20 | 40 |
| Ctrl vector + T157A-HA | 5.67 ± 0.13 | 27.91 ± 2.88 | 6 | 16 | 32 | |
| shRNA-PAK1 + HA | 3.55 ± 0.11 | −28.68 ± 9.17 | 8 | 20 | 40 | |
| shRNA-PAK1 + T157A-HA | 4.47 ± 0.12 | 1.00 ± 2.63 | 7 | 18 | 36 | |
| shRNA-ARF6 + HA | 3.25 ± 0.08 | −26.51 ± 1.74 | 5 | 14 | 28 | |
| Mature | Ctrl vector + HA | 4.80 ± 0.13 | 0 ± 2.69 | 9 | 24 | 48 |
| Ctrl vector + T157A-HA | 3.36 ± 0.11 | −29.95 ± 2.19 | 7 | 18 | 36 | |
| shRNA-PAK1 + HA | 4.24 ± 0.11 | −11.61 ± 2.19 | 5 | 14 | 28 | |
| shRNA-PAK1 + T157A-HA | 4.00 ± 0.14 | −16.67 ± 2.81 | 6 | 16 | 32 | |
| shRNA-ARF6 + HA | 3.75 ± 0.11 | −21.77 ± 2.26 | 8 | 20 | 40 |