TABLE 3.
Summary of FPR response profiles for 21 bacterial signal peptides identified in this study
Listed are sequences, sources, pathogenicity, frequency of database hits for residues 1–6 or 1–4, and the response profiles of hFPR1, hFPR2, hFPR3, mFpr1, mFpr2, and mFpr-rs1 for 21 N-terminal peptide fragments. Database hits refer to the number of identical sequence entries in the signal peptide database for the first four or six amino acids of a given signal sequence. Accession numbers refer to the UniProt database. Quantification of receptor sensitivity: Full large circles, activation threshold ≤100 nm; full small circles, activation threshold ≤1000 nm; open small circles, activation threshold ≤30,000 nm; minus sign, no response at 30 μm. n.d., no data.