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. 2015 Feb 2;290(12):7647–7657. doi: 10.1074/jbc.M114.595579

TABLE 1.

GO terms up-regulated in double-TG db/db islets

GO Term Counts in selectiona Counts in totalb Corrected p value
%
Endopeptidase inhibitor activity 7.94 0.53 3.67.E-16
Peptidase inhibitor activity 7.94 0.57 1.45.E-15
Serine-type endopeptidase inhibitor activity 6.50 0.39 4.06.E-14
Enzyme inhibitor activity 8.66 0.86 4.36.E-14
Oxidoreductase activity 13.72 2.76 4.90.E-13
Monooxygenase activity 6.50 0.48 1.64.E-12
Catalytic activity 40.07 20.03 9.26.E-12
Iron ion binding 6.50 0.70 7.06.E-10
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3.25 0.11 7.18.E-09
Enzyme regulator activity 11.19 2.72 1.46.E-08
Heme binding 4.69 0.43 8.54.E-08
Aromatase activity 2.89 0.11 1.66.E-07
Tetrapyrrole binding 4.69 0.46 1.90.E-07
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 5.05 0.55 1.92.E-07
Lipid binding 6.86 1.34 2.80.E-06
Lipid transporter activity 2.89 0.16 4.31.E-06
Electron carrier activity 3.61 0.42 6.53.E-05
Glutathione transferase activity 2.17 0.11 9.97.E-05
Cofactor binding 5.05 0.95 1.11.E-04
Fatty acid transporter activity 1.44 0.03 1.31.E-04

a Refers to the percentage of genes in the input entity list that have that GO term.

b Refers to the percentage of genes in the all entities list that have that GO term.

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