TABLE 1.

Zoxazolamine paralysis test

Zoxazolamine-induced paralysis is augmented in Abcb6^−/− mice given a single injection (intraperitoneally) of 300 mg/kg zoxazolamine. The data grouped together are from two independent experiments with six mice per group per experiment.

Abcb6+/+

1/12 > 1 h paralysis; recovered

2/12 > 2 h paralysis; recovered

8/12 > 4 h paralysis; recovered

1/12 > 6 h paralysis; recovered

Abcb−/−

12/12 > 12 h paralysis; recovered