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. 2015 Feb 10;290(12):7918–7929. doi: 10.1074/jbc.M114.622811

FIGURE 2.

FIGURE 2.

Impaired ScTx-induced constriction in arteries from WT HFD mice. Representative diameter recordings from pressurized (60 mm Hg) WT cerebral arteries from LFD and HFD mice before and after (A) psora-4 (500 nm) or (B) ScTx (50 nm). C, bar plot summarizing arterial tone in WT LFD (n = 5 arteries from 5 mice) and HFD (n = 5 arteries from 5 mice) arteries in the absence (−) and presence (+) of psora-4 (C). D, arterial tone in the absence (−) or presence (+) of ScTx in WT LFD (n = 7 arteries from 5 mice) and HFD (n = 7 arteries from 6 mice) arteries. E, amalgamated data of arterial tone from WT LFD (n = 8 arteries from 5 mice) and HFD (n = 10 arteries from 5 mice) at 60 mm Hg in response to 60 mm extracellular K+. *, p < 0.05.