Table 2.
Polythiophene (PTh)- and PTh-derivative-based DNA sensors and their performance in the detection of DNA hybridization.
| Matrix | Immobilization Method | Detection Method | Detection Limit | Sensitivity | Ref. |
|---|---|---|---|---|---|
| PTh | Covalent | Fluorescence | - | - | [144] |
| Poly(3′-carboxyl-5,2′,5′,2″-terthiophene) | Covalent | EIS | - | 5.608 (ng/cm2)/Hz | [146] |
| Poly(thiophen-3-yl-acetic acid 1,3-dioxo-1,3-dihydro-isoindol-2-yl ester | Covalent | CV | 1 nmol | 0.62 μA/nmol | [149] |
| Poly (3-[(S)-5-amino-5-carboxyl-3-oxapentyl]-2,5-thiophenylene hydrochloride) | Hydrogen bond | Fluorometric | 1 × 10−2 nmol | - | [151] |
| Cationinc PTh | Covalent | Fluorometric | 3.6 × 10−13 nM | - | [152] |
| Poly(5,2′:5,2″-terthiophene-3′-carboxylic Acid) | Covalent | Electrophoresis | 1.14 × 10−4 nM | 0.20 nA (fg/μL)−1 | [153] |
| PTh functionalized- methylene blue | HS-DNA bind on Au via Au-thiol chemistry | DPV | - | - | [156] |