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Effects of systemic treatment with memantine (0, 1.25, 2.5, 5, 10 mg/kg, i.p.) on 1 h food self-administration (n=17) (a). Effects of systemic treatment with memantine (0, 10 mg/kg, i.p.) on high rate of responding for Chow A/I induced by food restriction (n=10) (b). Data represent M±SEM. Symbols (*) denote significant difference from the vehicle-treated Palatable food group p⩽0.05 (Newman–Keuls).
