Table 1. Demographic, Neuropsychological and Clinical Characteristics of APOE ɛ4 Carriers and Non-Carriers.

	APOE ɛ4 carriers (n=35)	APOE ɛ4 non-carriers (n=40)	F/T-value (χ2)	p-value
Age (years)	67.26±7.62	64.45±7.30	1.63	0.11a
Male/female	17/18	19/21	0.01	1.00b
Education (years)	11.31±3.23	10.75±3.13	0.77	0.44a
General mental status
MMSE	27.11±1.95	27.30±1.52	0.01	0.93
Memory function
AVLT-delay recall	4.23±2.95	3.68±2.61	0.42	0.52
ROCF-delay recall	11.11±6.79	10.53±6.87	0.01	0.92
Backward digit span	4.45±1.504	3.87±1.25	2.54	0.12
Visuo-spatial processing
ROCF-Copy	33.06±3.77	32.83±2.73	0.61	0.44
CDT	24.80±3.99	23.55±3.71	0.13	0.72
Language
CVFT	43.51±10.76	40.23±7.91	1.52	0.22
BNT	23.71±3.87	23.38±4.02	0.01	0.94
Attention
SDMT	31.83±11.70	33.08±10.89	0.37	0.55
SCWT-B Time	41.77±10.27	39.68±7.01	0.52	0.47
TMT-A time (s)	64.71±34.71	55.56±24.86	1.06	0.31
Executive function
SCWT C-B Time	43.26±18.65	42.85±26.68	0.70	0.41
TMT-B time(s)	191.57±73.78	177.58±65.38	2.68	0.11
Lipid indicators
TC (mmol/l)	4.96±1.64	5.32±1.02	1.22	0.27
TG (mmol/l)	1.69±1.01	2.38±3.49	1.20	0.28
HDL (mmol/l)	1.30±0.32	1.32±0.31	0.44	0.51
LDL (mmol/l)	2.91±1.12	3.34±0.87	2.19	0.15

Abbreviations: AVLT, auditory verbal learning test; BNT, Boston naming test; CDT, clock-drawing test; CVFT, category verbal fluency test; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MMSE, Mini Mental-Status examination; ROCF, Rey–Osterrieth complex figure test; SCWT, stroop color and word test; SDMT, symbol digit modalities test; TC, total cholesterol; TG, triglyceride; TMT, trail making test.

Values are mean±SD or number of participants. The comparison of neuropsychological scores, glucose, and lipid levels between the two groups was performed with an analysis of covariance.

^aThe p-value for age and education were obtained using an independent two-sample t-test.

^bThe p-value for sex was obtained using a χ² test.