Table 1.

Changes in Effector Cell Function in Postinfluenza Bacterial Pneumonia

Cellular effector	Change in function
Alveolar macrophage	↓ Phagocytosis
	↓ Scavenger receptor expression
	↕ Cytokine/chemokine expression
Neutrophil	↕ Recruitment
	↓ Phagocytosis
	↓ Killing
	↓ Respiratory burst
	↑ Apoptosis
Natural killer cell	↓ Recruitment
	↓ TNF production
Airway/alveolar epithelial cell	↑ PAF receptor
	↑ Apoptosis
	↑ Bacterial adhesion

Abbreviations: PAF, platelet-activating factor; TNF, tumor necrosis factor.