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Geometry and fiber directions in 3D left ventricle with varied wall thickness. (A) Control and HFpEF concentric hypertrophic geometries—NORMAL (green, 9 mm), MILD (red, 12 mm), MODERATE (blue, 15 mm) and SEVERE (yellow, 18 mm). (B) Fiber direction. (C) Sheet direction. (D) Sheet-normal or cross-sheet direction.
