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. 2015 Mar 20;6:78. doi: 10.3389/fphys.2015.00078

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Copyright © 2015 Adeniran, MacIver, Hancox and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ca²⁺ handling and post-rest properties in HFpEF. (Ai,Bi) Diastolic Ca²⁺ level in HFpEF relative to control at 1 Hz (Ai) and 2 Hz (Bi) pacing rates. (Aii,Bii) SR Ca²⁺ content level in HFpEF relative to control at 1 Hz (Aii) and 2 Hz (Bii) pacing rates. (Aiii,Biii) Resting tension in HFpEF relative to control at 1 Hz (Aiii) and 2 Hz (Biii) pacing rates. (Aiv,Biv) Peak systolic tension in HFpEF relative to control at 1 Hz (Aiv) and 2 Hz (Biv) pacing rates. (Av,Bv) SR Ca²⁺ Ca leak in HFpEF relative to control at 1 Hz (Av) and 2 Hz (Bv) pacing rates.