Table 3. Outcome of multi-targeted vs. mono-targeted TKIs in NSCLC.
Study | Drug | n | Median PFS (week) | Median OS (week) | ORR (%) | DCR (%) |
---|---|---|---|---|---|---|
Socinski | Sunitinib | 63 | 11.3 | 24 | 9.5 | 52 |
Blumenschein | Sorafenib | 52 | 11.9 | 29 | 0 | 59 |
Ronald B | Vandetanib | 83 | 11 | 24 | 8 | 45 |
BR21 | Erlotinib | 488 | 9.4 | 28.7 | 6.9 | 43.0 |
Interest | Gefitinib | 659 | 9.4 | 32.6 | 9.7 | 45.8 |
DCR: disease control rate.