Table 2. Lung cancer cell lines.
| Cell line | NCI-H1299 | A549 | NCI-H460 | NCI-H358 |
|---|---|---|---|---|
| Histology | NSCLC | Ad | La | BAC |
| Mutation | ||||
| EGFR | wt | wt | wt | wt |
| KRAS | wt | mut | mut | mut |
| p53 | del | wt | wt | del |
| Sensitivity to drug IC50 (μM) | ||||
| CDDP | 16.60 | 33.90 | 0.800 | 21.50 |
| Paclitaxel | 0.02 | 0.03 | 0.008 | 0.05 |
| 5FU | 0.20 | 1.90 | 0.600 | 4.70 |
| Gemcitabine | 0.04 | 0.01 | 0.008 | >0.10 |
| Gefitinib | 29.60 | 2.90 | 14.100 | 5.40 |
| Surface marker | ||||
| HLA | ++ | + | ++ | ++ |
| CD54 | + | – | + | |
| CD166 | + | + | ++ | ++ |
| MICA | ++ | + | ++ | – |
| Sensitivity to γδ T cell | + | + | +++ | ++ |
Abbreviations: NSCLC, non-small-cell lung cancer; Ad, adenocarcinoma; La, large cell carcinoma; BAC, bronchioloalveolar carcinoma; wt, wild type; mut, mutation; del, deletion.