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. 2013 Aug;2(4):273–283. doi: 10.3978/j.issn.2218-6751.2013.03.12

Table 2. Genetic and chromosomal aberrations associated with CNS metastasis.

Locus Alteration References
EGFR Mutation (23-25)
EGFR Copy number gain (26)
KRAS Mutation (25,27-29)
Ch2q Loss (30,31)
Ch4q12-q32 Loss (32)
Ch5q35 Amplification (33)
Ch10q23 Amplification (33)
Ch11p15 Imbalance (34)
Ch17q23-24 Amplification (33)
Ch18q Loss (30,31)
Ch22q Loss (30,31)