Figure 2.
Tumor foci on pleura from three treatment groups. Sixteen days after the LLC inoculation, mice in each group were anesthetized and sacrificed. A significant reduction in the number of pleural tumors was observed in the H-ITCZ treated group (C) compared with the H-β-C (A) and the L-ITCZ (B) groups. A significant difference was also observed between the L-ITCZ group and the H-β-C group (D). Columns represent the mean value of each group, bars ± SD. ***P<0.001. LLC, Lewis lung carcinoma; H-β-C, hydroxypropyl-β-cyclodextrin; L-ITCZ, low itraconazole; H-ITCZ, high itraconazole.
