Figure 4.

VEGF-C expressions in MPEs from the H-β-C, L-ITCZ and H-ITCZ groups by ELISA. VEGF-C expression in the H-ITCZ-treated group significantly decreased compared with the H-β-C and L-ITCZ groups. A significant difference was also observed between the L-ITCZ group and H-β-C group. Columns represent the mean value of each group, bars ± SD. ***P<0.001, **P<0.01. VEGF-C, vascular endothelial growth factor-C; MPE, malignant pleural effusion; ELISA, enzyme-linked immunosorbent assay; H-β-C, hydroxypropyl-β-cyclodextrin; L-ITCZ, low itraconazole; H-ITCZ, high itraconazole.