Figure 6.
IHC staining of VEGF-C expressions in tumors on pleura from three treatment groups. VEGF-C expression was significantly reduced in the H-ITCZ-treated group (C) compared with the H-β-C group (A) or the L-ITCZ group (B). A significant difference was also observed between the L-ITCZ group and H-β-C group (D). Columns represent the mean value of each group, bars ± SD. ***P<0.001, **P<0.01, *P<0.05. IHC, immunohistochemistry; VEGF-C, vascular endothelial growth factor-C; H-β-C, hydroxypropyl-β-cyclodextrin; L-ITCZ, low itraconazole; H-ITCZ, high itraconazole.
