Table 4. Multivariate Cox regression analysis of survival in 181 patients with advanced NSCLC.
| Variables | PFS |
PPS |
OS |
|||||
|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |||
| Age (years) | 1.058 (0.748-1.496) | 0.75 | 1.394 (0.951-2.044) | 0.089 | 1.220 (0.827-1.800) | 0.315 | ||
| Sex | 0.962 (0.635-1.458) | 0.856 | – | – | – | – | ||
| Smoke status | 1.231 (0.814-1.860) | 0.325 | – | – | – | – | ||
| loss of weight | 1.302 (0.827-2.049) | 0.254 | 1.309 (0.781-2.194) | 0.307 | 1.324 (0.795-2.206) | 0.281 | ||
| Tumor diameter | 1.258 (0.855-1.851) | 0.244 | 1.533 (0.989-2.376) | 0.056 | 1.511 (0.976-2.338) | 0.064 | ||
| Histology | 1.201 (0.845-1.709) | 0.308 | – | – | 1.404 (0.974-2.024) | 0.069 | ||
| Stage | – | – | 1.673 (1.056-2.651) | 0.028 | – | – | ||
| Clinical response | 6.555 (4.142-10.372) | 0 | 1.568 (0.998-2.463) | 0.051 | 2.803 (1.752-4.483) | 0 | ||
| SUVmax | 1.086 (0.671-1.756) | 0.737 | 0.955 (0.568-1.607) | 0.863 | 1.003 (0.591-1.702) | 0.991 | ||
| SUVmax/tumor size | 1.438 (0.936-2.207) | 0.097 | 1.476 (0.905-2.407) | 0.119 | 1.656 (1.000-2.742) | 0.05 | ||
NSCLC, non-small cell lung cancer; PFS, progression free survival; PPS, post-progression survival; OS, overall survival; SUVmax, maximum standardized uptake value.