Table 2. Summary of selected studies that evaluated thermal ablation treatment of inoperable patients with stage I NSCLC.

	Study type		Tumor stage	Mean tumor size (cm)	Overall survival (%)				Cancer-specific survival (%)
	Study type		Tumor stage	Mean tumor size (cm)	1-yr	2-yr	3-yr	5-yr	1-yr	2-yr	3-yr	5-yr
RFA
[Simon et al., 2007] (14)	Retrospective		56 stage IA; 19 stage IB	3.0	78	57	36	27
[Pennathur et al., 2007] (13)	Retrospective		11 stage IA; 8 stage IB	2.6	95	68
[Lencioni et al., 2008] (12)	Prospective, intention-to-treat		10 stage IA; 3 stage IB	2.2		75				92
[Lanuti et al., 2009] (11)	Retrospective		29 stage IA; 5 stage IB	2.0	85	78	47		82	57	39
[Hiraki et al., 2011] (10)	Retrospective		38 stage IA; 12 stage IB	2.1	94	86	74		100	93	80
[Ambrogi et al., 2011] (8)	Prospective, intention-to-treat		44 stage IA; 15 stage IB	2.6					89		59	40
Microwave ablation
[Liu and Steinke, 2013] (49)	Retrospective		15 stage I	2.5	N/A				N/A
Cryoablation
[Yamauchi et al., 2012] (19)	Retrospective		34 stage IA (29 T1aN0, 5 T1bN0)	1.4		88	88
RFA, Cryoablation
[Zemlyak et al., 2010] (50)	Retrospective	RFA	12 stage I	Not reported			88				88
[Zemlyak et al., 2010] (50)	Retrospective	Cryo	27 stage I	Not reported			77				90