Table 3.

PRCP Inhibition Data (N-Substituted-Pro-NH Dodecylamides)

Cpnd	R	rPRCP Ki (µM)	PRCP-dependent PK activation on HPAEC Ki (µM)
5		NE	NE
6	H	61.54 ± 8.2	477 ± 28.7
7a		NE	NE
7b		NE	NE
7c		NE	NE
7d		43.7 ± 5.2	17.36 ± 3.2

NE; No effect