Table 4.
PRCP Inhibition Data (Azetidine-NH Dodecylamides)
 | |||
|---|---|---|---|
| Cpnd | R | rPRCP Ki (µM) |
PRCP-dependent PK activation on HPAEC Ki (µM) |
| 10 | H | 195.1 ± 15.4 | 50.14 ± 8.1 |
| 12 |  |
108.92 ± 12.5 | 29.6 ± 3.6 |
| 14 |  |
84.92 ± 7.6 | 60.43 ± 7.2 |
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