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. Author manuscript; available in PMC: 2015 Mar 20.
Published in final edited form as: Mol Pharmacol. 2002 Nov;62(5):1249–1257. doi: 10.1124/mol.62.5.1249

Fig. 9.

Fig. 9

[3H]MRS2279 binding in intact human platelets. Freshly outdated human platelets from a single donor with blood type B (A) or blood type O (B) were washed as described under Materials and Methods. Approximately 109 washed platelets/assay were incubated 30 min at 4°C with 6 nM [3H]MRS2279 and increasing concentrations of the P2Y1-R antagonists A3′P5′P (■), MRS2179 (▲), or MRS2279 (▼) (A). Approximately 109 washed platelets/assay were incubated for 50 min at 4°C with the indicated concentrations (1–65 nM) of [3H]MRS2279 (B). The data are plotted as specific binding. B, inset, Scatchard transformation of the data.