Table 3.

Number of adverse events reported in ≥ 5% of subjects by treatment group

AE description	Synvisc-One n = 32	Hydros n = 32	Hydros-TA n = 34
Any TEAE, n (%)	23 (72)	24 (75)	21 (62)
Arthralgia, n (%)	8 (25)	11 (34)	7 (21)
Joint Swelling, n (%)	2 (6)	3 (9)	2 (6)
Joint Stiffness, n (%)	2 (6)	3 (9)	0
Back Pain, n (%)	3 (9)	1 (3)	1 (3)
Muscle Spasms, n (%)	1 (3)	0	3 (9)
Arthritis, n (%)	0	2 (6)	0
Headache, n (%)	8 (25)	6 (19)	4 (12)
Nasopharyngitis, n (%)	3 (9)	1 (3)	1 (3)
Nausea, n (%)	1 (3)	2 (6)	1 (3)
Meniscus Lesion, n (%)	1 (3)	0	2 (6)
Tendon Pain, n (%)	2 (6)	0	0

Abbreviations: AE = Adverse Event; TEAE = Treatment-Emergent Adverse Event.