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. 2014 Dec 24;15(1):1178. doi: 10.1186/1471-2164-15-1178

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© Yip et al.; licensee BioMed Central. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Statistical significance of the negative correlations between the expression levels of miRNAs and mRNAs in the same MTBs. The p-values were computed based on the expressed union sets with TarBase interactions, for (a) the high-confidence set and (b) the high-coverage set as compared to a random background sampled from all expressed mRNAs and miRNAs; and (c) the high-confidence set and (d) the high-coverage set as compared to a background consisting of miRNA-mRNA pairs with interactions in the input network but are not in same MTBs. In the figures, 1E-16 represents the smallest p-value that could be outputted by our program. MTB types with no identified MTBs are omitted.