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. 2014 Dec 24;15(1):1178. doi: 10.1186/1471-2164-15-1178

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© Yip et al.; licensee BioMed Central. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Comparing MTBs with the miRNA regulatory modules (MRMs) identified by the Yoon and De Micheli method. The p-values were computed by comparing the fractions of correlations more negative than the threshold t of miRNA-mRNA pairs within MTBs, as compared to those from the MRMs. In the figure, 1E-16 represents the smallest p-value that could be outputted by our program.