Figure 5.

The apoptosis-inducing effects of Qu-M and free-Qu in a dose-dependent manner on CT26 cells in vitro.

Notes: The CT26 cells were incubated with Qu-M, free-Qu, NS, and EM for 48 hours, and Annexin-V- and PI-stained cells were determined by flow cytometry.

Abbreviations: Qu-M, quercetin-loaded MPEG–PCL nanomicelles; free-Qu, free quercetin; NS, normal saline; EM, empty MPEG–PCL nanomicelles; MPEG–PCL, monomethoxy poly(ethylene glycol)–poly(ε-caprolactone); PI, propidium iodide; FITC, fluorescein isothiocyanate.