Table III.
Clinicopathological factor | n | Five-year survival rate | P-value |
---|---|---|---|
Peritoneal dissemination | |||
p0 | 47 | 0.893 | <0.0001 (p0 vs. 1) |
p1 | 3 | 0.000 | |
Stage | |||
I/II | 41 | 0.975 | <0.0001 (I/II vs. III/IV) |
III/IV | 9 | 0.222 | |
Tumor size (mm) | |||
<50 | 38 | 0.920 | 0.0001 (<50 vs. >50) |
>50 | 12 | 0.583 | |
Venous invasion | |||
v0 | 43 | 0.906 | 0.0011 (v0 vs. 1/2) |
v1/2 | 7 | 0.429 | |
Lymphatic invasion | |||
ly0/1 | 43 | 0.906 | 0.0017 (ly0/1 vs. 2/3) |
ly2/3 | 7 | 0.429 | |
Lymph node metastasis | |||
n0/1 | 45 | 0.888 | 0.0056 (n0/1 vs. 2) |
n2 | 5 | 0.400 | |
Infiltrative growth pattern | |||
IFNα/β | 32 | 0.937 | 0.0083 (IFNα/β vs. γ) |
IFNγ | 17 | 0.647 | |
c-Met expression | |||
(−) | 25 | 0.920 | 0.0342 [(−) vs. (+)] |
(+) | 25 | 0.758 | |
serum HGF (pg/ml) | |||
<400 | 36 | 0.887 | 0.0558 (<400 vs. >400) |
>400 | 14 | 0.714 | |
Histological type | |||
well/mod | 23 | 0.920 | 0.1793 (well/mod vs. por/sig) |
poor/sig | 25 | 0.756 | |
Depth | |||
m | 13 | 0.917 | 0.2649 (m vs. sm/mp/ss/se) |
sm/mp/ss/se | 37 | 0.811 | |
HGF expression | |||
(−) | 14 | 0.929 | 0.5385 [(−) vs. (+)] |
(+) | 36 | 0.806 |
HGF, hepatocyte growth factor; m, mucosa; sm, submucosa; mp, muscularis propria; ss, subserosa; s, serosa; INF, infiltrative growth pattern; INFα, expansive type (tumor margin is clear); INFβ, intermediate type; INFγ, invasive type (tumor margin is unclear); well, well-differentiated tubular adenocarcinoma; mod, moderately differentiated tubular adenocarcinoma; poor, poorly differentiated adenocarcinoma; sig, signet-ring cell carcinoma; muc, mucinous adenocarcinoma; pap, papillary adenocarcinoma.