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. 2015 Jan 7;11(5):3337–3343. doi: 10.3892/mmr.2015.3148

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Copyright © 2015, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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Lv-mediated knockdown of SNRPN inhibited the colony-forming ability of Daoy cells. (A) Representative images of colony formation in Daoy cells with three treatments (Con, Lv-shCon and Lv-shSNRPN) are shown. (B) The size of each colony was significantly smaller in the Lv-shSNRPN groups as compared with the Lv-shCon and uninfected groups (scale bar, 125 μm). (C) The average number of colonies are presented as a bar chart. (^***P<0.001). Lv, lentivirus; SNRPN, small nuclear ribonucleoprotein-associated polypeptide N; Con, control, sh, short hairpin.