Table II.

Classification of other factors associated with IL-1β in Alzheimer’s disease.

Type	Factors
Cytokines	MCP-1, MIP-1β, MIP-1α, CD36, G-CSF, TGF-β1, EGF, IL-13, oncostatin M, IL-2, IL-18, sTNF-R1
Other immune factors	C4, C1-lnh, NALP1
Neurotransmitters	BDNF, NT-3
Signal factor	BACE1, BACE2, IRAK-1, IRAK-2, Cox-IV, TLR, IKK, IκB, P65, FPR, MAChR, AP-1
Hormone	PGE1, norepinephrine F2-isoprostane
Lipid	RAGE, DHA, EPA, PUFAs
Globulin	Perlecan

MCP, monocyte chemotactic protein; MIP, macrophage inflammatory protein; TGF, transforming growth factor; EGF, endothelial growth factor; G-CSF, granulocyte colony stimulating factor; IL, interleukin; TNF, tumor necrosis factor; NALP, NACHT leucine-rich repeat protein; BDNF, brain-derived neurotrophic factor; NT, neurotrophin; BACE, beta-secretase; IRAK, interleukin-1 receptor-associated kinase; Cox, cytochrome C oxidase; TLR, toll-like receptor; IKK, inhibitor of nuclear factor kappa-B kinase subunit alpha; IκB, inhibitor of kappa B; FPR, formyl peptide receptor; MAChR, muscarinic acetylcholine receptor; AP, activator protein; PGE, prostaglandin E; RAGE, receptor for advanced glycation end-products; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; PUFA, polyunsaturated fatty acid.