Table 3. Operating characteristics in diagnosing pancreatic solid malignant lesions in the two groups (n = 163).
| Sensitivity,% (95% CI) | Specificity,% (95% CI) | PPV,% (95% CI) | NPV,% (95% CI) | Accuracy (95% CI) | AUC (95% CI) | |
|---|---|---|---|---|---|---|
| CH-EUS Group (n = 58) | 81.6 (65.7–92.3) | 100.0 (83.2–100.0) | 100.0 (88.8–100.0) | 74.1 (53.7–88.9) | 87.9 (79.5–96.3) | 0.908 (0.803–0.969) |
| CH-EUS Group* (n = 58) | 89.5 (75.2–97.1) | 100.0 (83.2–100.0) | 100.0 (89.7–100.0) | 83.3 (62.6–95.3) | 93.1 (86.6–99.6) | 0.947 (0.855–0.989) |
| CH-EUS Group# (n = 58) | 92.1 (78.6–98.3) | 100.0 (83.2–100.0) | 100.0 (90.0–100.0) | 87.0 (66.4–97.2) | 94.8 (89.1–100.0) | 0.961 (0.874–0.994) |
| EUS Group (n = 105) | 70.8 (58.9–81.0) | 100.0 (89.4–100.0) | 100.0 (93.0–100.0) | 61.1 (46.9–74.2) | 80.0 (72.3–87.7) | 0.854 (0.772–0.915) |
| EUS Group* (n = 105) | 77.8 (66.4–86.7) | 100.0 (89.4–100.0) | 100.0 (93.6–100.0) | 67.4 (52.5–80.1) | 84.8 (77.9–91.7) | 0.889 (0.813–0.942) |
| EUS Group# (n = 105) | 80.6 (69.5–88.9) | 96.9 (84.2–99.9) | 98.3 (90.9–100.0) | 69.6 (54.2–82.3) | 85.7 (79.0–100.0) | 0.888 (0.811–0.941) |
CH-EUS, contrast-enhanced harmonic endoscopic ultrasonography; EUS, endoscopic ultrasonography group; AUC, area under receiver operating characteristic curve; PPV, positive predictive value; NPV, negative predictive value; 95% CI, 95% confidence interval.
*Suspicious cytology considered as diagnostic of malignancy.
#Atypical/suspicious cytology considered as a diagnostic of malignancy.