Figure 2.

Different levels of CD91 identify two monocyte-derived dendritic cell (moDC) subpopulations. Immature moDCs were stained for surface expression of CD91 and activation/maturation markers. (a) Representative flow cytometric analysis showing the gating strategy used to define CD91^dim and CD91^bright moDCs. (b) Graphs show the mean fluorescence intensity (MFI) of CD80, CD86, CD40, CD83, CCR7 and HLA-DR molecules in CD91^dim (white bars) and CD91^bright (black bars) moDCs from 11 independent experiments. Data shown as mean ± SE. *P < 0·05, **P < 0·01.