Figure 7.

(a–g) Effect of anti-Gr-1 and anti-tumour necrosis factor-α (TNF-α ) treatment on colonic inflammatory cytokine expression during C. difficile colitis. Host gene expression was measured via quantitative PCR as described in the methods; n ≥ 7 per group. Data are shown as mean ± SEM fold change gene expression of C. difficile infected (black bars), C. difficile infected and anti-Gr-1 treated (white bars), and C. difficile infected and anti-TNF-α treated (grey bars) animals as compared with untreated mice. CDI = C. difficile infected *P < 0·05 compared with untreated animals. Brackets indicate P < 0·05 for the differences between the indicated groups.