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. 2015 Mar 20;10(3):e0120720. doi: 10.1371/journal.pone.0120720

Table 2. Univariate and Multivariate Analyses for Associations between Refractive Error and Childhood Concomitant Esotropia.

Univariate Multivariate*
OR CI p OR CI p
Age group
 3 y Ref Ref
 4 y 1.52 0.44 5.19 0.507 1.37 0.36 5.17 0.638
 5 y 1.80 0.53 6.09 0.346 2.12 0.57 7.88 0.264
 6 y 3.94 0.98 15.85 0.054 2.70 0.54 13.53 0.227
Sex
 Male Ref Ref
 Female 0.92 0.51 1.66 0.779 0.85 0.43 1.64 0.62
SE anisometropia(D)
 <0.50 Ref Ref
 0.50-<1.00 19.74 9.43 41.32 <0.001 3.15 1.07 9.29 0.037
 > = 1.00 34.17 16.10 72.52 <0.001 7.41 2.50 21.93 <0.001
J0 anisometropia(D)
 <0.25 Ref Ref
 0.25-<0.50 9.09 3.97 20.85 <0.001 1.14 0.40 3.27 0.802
 > = 0.50 5.78 1.36 24.59 0.018 0.46 0.07 2.80 0.40
J45 anisometropia(D)
 <0.25 Ref Ref
 0.25-<0.50 7.67 2.67 21.98 <0.001 1.83 0.53 6.36 0.344
 > = 0.50 3.64 0.49 27.12 0.208 0.57 0.05 6.10 0.645
SE refractive error(D)
 0.00-<1.00 Ref Ref
 -1.0-<0.00 0 0.999 0 0.998
 <-1.00 15.15 1.93 119.28 0.01 3.70 0.31 43.70 0.299
 1.00-<2.00 8.03 3.12 20.71 <0.001 3.15 0.82 12.10 0.095
 2.00-<3.00 23.81 9.99 56.79 <0.001 9.30 2.63 32.96 0.001
 3.00-<4.00 25.64 5.61 117.21 <0.001 9.28 1.48 58.13 0.017
 4.00-<5.00 47.63 10.00 226.81 <0.001 14.57 2.32 91.65 0.004
 > = 5.00 416.72 145.64 1192.33 <0.001 180.82 36.37 898.89 <0.001
Astigmatism (D)
 0.00-<0.50 Ref Ref
 0.5-<1.00 45.95 18.47 114.33 <0.001 3.06 0.77 12.18 0.114
 > = 1.00 12.00 3.49 41.24 <0.001 0.34 0.05 2.49 0.29
 <0.00 11.67 5.88 23.18 <0.001 1.06 0.34 3.28 0.919

D = diopters; J0 = power in the vertical or horizontal meridian; J45 = power in the oblique meridian; SE = spherical equivalent.

Odds ratios in boldface are statistically significant.

*Adjusted for all factors retained in the mutivariate analysis.