Table 1.
Patient demographics, peri- and post-operative course of patients who underwent laparoscopic and open liver resections for hepatocellular carcinoma
| LLR n = 43 (%) | OLR n = 86 (%) | Combined n = 129 (%) | P-value | |
|---|---|---|---|---|
| Gender | 0.110 | |||
| Male | 29 (67.4) | 69 (80.2) | 98 (76.0) | |
| Female | 14 (32.6) | 17 (19.8) | 31 (24.0) | |
| Age at resection (years; median, range) | 62.0 (30–86) | 63.0 (34–84) | 62.9 (30–86) | 0.521 |
| Underlying liver disease | 0.100 | |||
| HBV | 19 (44.2) | 52 (60.5) | 71 (55.0) | |
| HCV | 13 (30.2) | 18 (20.9) | 31 (24.0) | |
| Other (NASH, alcohol, undetermined) | 11 (25.6) | 16 (18.6) | 27 (20.9) | |
| Child–Pugh | 0.789 | |||
| A | 41 (97.6) | 81 (97.6) | 122 (97.6) | |
| B | 1 (2.4) | 2 (2.4) | 3 (2.4) | |
| Not available | 1 | 3 | 4 | |
| Clavien–Dindo Classification | 0.050 | |||
| Non-severe (Grade 1–2) | 10 (100.0) | 24 (72.7) | 34 (79.1) | |
| Severe (Grade 3–4) | 0 (0.0) | 9 (27.3) | 9 (20.9) | |
| No complication | 32 | 52 | 84 | |
| Not available | 1 | 1 | 2 | |
| Type of hepatic resection | ||||
| 1–2 segments | 21 (48.8) | 45 (52.3) | 66 (51.2) | 0.740 |
| 2 + segments | 22 (51.2) | 41 (47.7) | 63 (48.8) | |
| Resection margin | 1.000 | |||
| Positive | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| Negative | 43 (100.0) | 86 (100.0) | 129 (100.0) | |
| Not available | 0 | 0 | 0 | |
| Estimated blood loss (ml; median, range) | 300 (0–6500) | 700 (0–3500) | 600 (0–6500) | 0.004 |
| Incision to closure time (min; median, range) | 170 (88–536) | 197 (70–365) | 194 (88–536) | 0.610 |
| Complications | 0.067 | |||
| Yes | 10 (23.3) | 34 (39.5) | 44 (34.1) | |
| No | 33 (76.7) | 52 (60.6) | 85 (65.9) | |
| Conversion | ||||
| Yes | 6 (14.0) | NA | NA | NA |
| No | 37 (86.0) | |||
| Admission to ICU | 0.657 | |||
| Yes | 3 (7.0) | 8 (9.3) | 11 (8.5) | |
| No | 40 (93.0) | 78 (90.7) | 118 (91.5) | |
| 30-day readmission | 0.010 | |||
| Yes | 1 (2.3) | 16 (18.6) | 17 (13.2) | |
| No | 42 (97.7) | 70 (81.4) | 112 (86.8) | |
| ER visit in 3 months | 0.267 | |||
| Yes | 2 (4.7) | 9 (10.5) | 11 (8.5) | |
| No | 41 (95.3) | 77 (89.5) | 118 (91.5) | |
| Length of stay (days; median, range) | 5 (3–51) | 7 (5–77) | 7 (3–77) | <0.001 |
OLR, open liver resection; HBV, hepatitis B virus;HCV, hepatitis C virus; NASH, non-alcoholic steatohepatitis; ICU, intensive care unit.