Table 2.
Characteristics of Patients with PTC ≤ 2 cm as the First and Only Primary Tumors by Thyroid Cancer-Related Mortality, SEER, 1988–2007
| Patient Characteristics | Thyroid Cancer-Related Mortality
|
Total (%) | P | |
|---|---|---|---|---|
| Alive (%)1 | Dead (%) | |||
|
| ||||
| No. of patients (%) | 30,031 (99.5) | 153 (0.5) | 30,184 | |
|
| ||||
| Gender | < 0.01 | |||
| Male | 5,325 (17.7) | 46 (30.1) | 5,371 (17.8) | |
| Female | 24,706 (82.3) | 107 (69.9) | 24,813 (82.2) | |
|
| ||||
| Age, years | < 0.01 | |||
| < 45 | 14,520 (48.4) | 12 (7.8) | 14,532 (48.1) | |
| ≥45 | 15,511 (51.6) | 141 (92.2) | 15,652 (51.9) | |
|
| ||||
| Race/ethnicity (16) | 0.03 | |||
| White | 25,213 (84.5) | 118 (77.1) | 25,331 (84.4) | |
| Black | 1,327 (4.4) | 8 (5.2) | 1,335 (4.4) | |
| Other | 3,309 (11.1) | 27 (17.6) | 3,336 (11.1) | |
|
| ||||
| Tumor size | < 0.01 | |||
| ≤1 cm | 16,194 (53.9) | 63 (41.2) | 16,257 (53.9) | |
| >1–2 cm | 13,837 (46.1) | 90 (58.8) | 13,927 (46.1) | |
|
| ||||
| Extrathyroidal extension | < 0.01 | |||
| Yes | 3,337 (11.2) | 53 (40.8) | 3,390 (11.3) | |
| No | 26,509 (88.8) | 77 (40.8) | 26,586 (88.7) | |
|
| ||||
| Lymph node metastasis | < 0.01 | |||
| Yes | 5,459 (27.7) | 68 (77.3) | 5,527 (27.9) | |
| No | 14,266 (72.3) | 20 (22.7) | 14,286 (77.3) | |
|
| ||||
| Distant metastasis | < 0.01 | |||
| Yes | 258 (1.1) | 22 (31) | 280 (1.1) | |
| No | 24,023 (98.9) | 49 (69) | 24,072 (98.9) | |
|
| ||||
| Surgery | 0.31 | |||
| Less than lobectomy | 221 (0.9) | 1 (1.4) | 222 (0.9) | |
| Lobectomy | 3,987 (16.4) | 7 (9.9) | 3,994 (16.4) | |
| Subtotal or total thyroidectomy | 20,080 (82.7) | 63 (88.7) | 20,143 (82.7) | |
|
| ||||
| Radiotherapy | < 0.01 | |||
| None | 15,949 (53.9) | 56 (37.8) | 16,005 (53.9) | |
| Radioisotopes | 12,787 (43.2) | 68 (45.9) | 12,855 (43.3) | |
| XRT2 | 301 (1) | 12 (8.1) | 313 (1.1) | |
| Combined XRT2 and radioisotopes | 105 (0.4) | 8 (5.4) | 113 (0.4) | |
| Other | 428 (1.4) | 4 (2.7) | 432 (1.5) | |
|
| ||||
| Median follow-up (range) in months | 53 (1–239) | 55 (1–199) | 54 (1–239) | 0.14 |
1
Percentage of parameter by mortality status
2
XRT: external radiotherapy