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. Author manuscript; available in PMC: 2016 Mar 18.
Published in final edited form as: Neuron. 2015 Mar 5;85(6):1200–1211. doi: 10.1016/j.neuron.2015.02.025

Figure 6. PAPP-AA mediates habituation through acute regulation of IGF signaling.

Figure 6

(A) Mean acoustic startle habituation percentage at 5 dpf of larvae treated with DMSO or 1μM SC79. Treatment period (dpf) indicated below bars. (B) Mean acoustic startle habituation percentage of 5 dpf larvae treated with 740 Y-P for 30 min prior to and during habituation assay. (C-D) Mean acoustic startle habituation percentage after 30 min treatment with BMS-754807 or DMSO at 5 dpf (C) or 12 dpf (D). *p<0.01, **p<0.001, ANOVA with Bonferonni correction versus DMSO treated larvae of the same genotype. N= number of larvae shown within bars. Error bars indicate SEM.